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Accuracy of noncompartmental pharmacokinetic parameters estimated from bolus injection and steady-state infusion data

โœ Scribed by Michael Looby; Michael Weiss


Book ID
112736776
Publisher
Springer
Year
1995
Tongue
English
Weight
717 KB
Volume
23
Category
Article
ISSN
1573-8744

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The steady-state and terminal volumes of distribution, as well as the mean residence time of drug in the body (V ss , V $ , and MRT) are the common pharmacokinetic parameters calculated using the drug plasma concentration-time profile C p (t) following intravenous (i.v. bolus or constant rate infusi