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Accumulation of p27Kip1 is associated with retinoic acid-induced growth arrest and neuronal differentiation of immortalized human neural progenitor cells

โœ Scribed by Zhao, Yongmei; Zhang, Haiyan; Xu, Qiuyan; Xu, Qunyuan


Book ID
123255448
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
57 KB
Volume
6
Category
Article
ISSN
1552-5260

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Human lung cancer cells, including small cell lung carcinoma (SCLC), frequently lose expression of retinoic acid receptor โค (RAR-โค) and are resistant to the growth inhibitory activity of all-trans retinoic acid (RA). To elucidate the role of RAR-โค in the growth regulation of SCLC by retinoids, we re