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Acceleration of pancreatic cancer development in the conditional KrasG12D mouse model by a high fat and high calorie diet

✍ Scribed by Moro, A.; Lugea, A.; Dawson, D.W.; Pandol, S.; Gukovskaya, A.; Rozengurt, E.; Hines, O.J.; Go, V.L.W.; Eibl, G.

Book ID
123026053
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
62 KB
Volume
13
Category
Article
ISSN
1424-3903

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## Abstract In previous studies, we demonstrated that high corn oil diets promote the development of 7,12‐dimethylbenz(α)anthracene (DMBA)‐induced mammary tumors. In this study, we have investigated whether modulation of gene expression is one of the mechanisms by which this high‐fat diet exerts su