Abundance of platelet-derived growth factors (PDGFs), PDGF receptors and activation of mitogen-activated protein kinases in brain decline with age
β Scribed by Yanhua Hu; Georg Schett; Yiping Zou; Hermann Dietrich; Qingbo Xu
- Book ID
- 117387024
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 506 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0169-328X
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Steady-state levels of rat central nervous system (CNS) platelet-derived growth factor (PDGF) A-and B-chain mRNAs were measured by a polymerase chain reaction method employing a synthetic gene internal standard, and the rates of transcription of PDGF A-and B-chain genes in CNS were estimated by a nu
## Abstract Plateletβderived growth factorβB (PDGFβB) and its receptors play essential roles in the complex process of blood vessel maturation and they therefore constitute promising targets for therapeutic strategies against blood vesselβrelated diseases. Additionally, they are involved in the aut