ABT-089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders
β Scribed by Lynne E. Rueter; David J. Anderson; Clark A. Briggs; Diana L. Donnelly-Roberts; Gary A. Gintant; Murali Gopalakrishnan; Nan-Horng Lin; Mark A. Osinski; Glenn A. Reinhart; Michael J. Buckley; Ruth L. Martin; Jeffrey S. McDermott; Lee C. Preusser; Terese R. Seifert; Zhi Su; Bryan F. Cox; Michael W. Decker; James P. Sullivan
- Book ID
- 109105645
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 150 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1080-563X
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## Abstract Neuronal nicotinic acetylcholine receptor (nAChR) agonists have been demonstrated to exhibit antinociceptive, antihyperalgesic, and antiallodynic effects across a range of preclinical models of pain. Yet, to date, no drugs have been successfully developed and approved for the treatment