Synthesis of 12(S),20-, 12(S),19(R)-, an
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Sukumar Manna; Jacques Viala; Pendri Yadagiri; J.R Falck
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Article
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1986
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Elsevier Science
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French
โ 231 KB
Enantiospecific syntheses of the ZO-and both 19-hydroxy metabolites of 12(S)-HETE were accomplished using readily available, chiral precursors. Recently, a new metabolite of 12(S)-hydroxyeicosatetraenoic (12-HETE) acid (1) was isolated from the coincubation of human platelets and neutrophils with ar