Absorption potential: Estimating the fraction absorbed for orally administered compounds

Toward a quantitative approach for the p

Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept

✍ Panayotis E. Macheras; Mira Y. Symillides 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 524 KB

An equation based on the absorption potential concept was developed. This enabled us to establish an approach for the quantitative prediction of the fraction of dose absorbed. Classification of drugs into three broad categories, according to their absorption potential values in relation to the fract