Absorption of paraquat by rat gut in vitro

✍ Scribed by Christian Steffen; Heribert Konder

• Book ID: 104726945
• Publisher: Springer-Verlag
• Year: 1979
• Tongue: English
• Weight: 245 KB
• Volume: 43
• Category: Article
• ISSN: 0340-5761
• DOI: 10.1007/bf00333616

✦ Synopsis

The absorption of radioactively labeled paraquat was measured in rat ileum, jejunum and colon by a micro everted sac technique (Semenza and Muhlhaupt, 1969). The absorption rate increased linearly over the range of concentrations measured (10(-5) to 10(-2) M) and was enhanced by nearly 50% in the absence of sodium ions. The absorption rate decreased in the order: ileum, jejunum, colon whereby in the colon still 65% of the values of the small intestine were observed.