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Absorption and Drug Development (Solubility, Permeability, and Charge State) || Introduction

✍ Scribed by Avdeef, Alex

Book ID
120008039
Publisher
John Wiley & Sons, Inc.
Year
2012
Tongue
English
Weight
101 KB
Edition
2
Category
Article
ISBN
1118057457

No coin nor oath required. For personal study only.

✦ Synopsis

Of the hundreds of thousands of compounds synthesized each year, most have almost no chance of becoming drugs. This problem exists because most molecules lack the drug-like properties necessary to enable them to be effective in vivo. To address this issue, Alex Avdeef's Absorption and Drug Development shows the reader how to examine a compound's pharmaceutical properties, emphasizing oral absorption. This book explains the different physicochemical methods currently used to analyze drug candidates and how to interpret these methods. Also included are physicochemical data for over 200 commercial drugs. With over 600 references and 100 drawings, this book is an excellent resource for the practical pharmaceutical chemist and those seeking a better understanding of physicochemical measurements.

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