Absolute configuration of (+)-methyl 8-methyl-8-azabicyclo[3.2.1]oct-2-ene-3-carboxylate
β Scribed by Clarke, Robert L.; Heckeler, Monica L.
- Book ID
- 127307039
- Publisher
- American Chemical Society
- Year
- 1978
- Tongue
- English
- Weight
- 548 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The synthesis of a d'carbapenem and two ,?-lactams possessing a Br-atom at the N-substituting center not involved in the lactam ring and bearing the carboxyl group is described. The ,?-lactams having this kind of Br-substitution are more susceptible to nucleophilic attack than those having a conjuga
The carbon and proton spectra of the title compound were completely assigned on the basis of COSY, HETCOR, DEPT and selective single-frequency decoupling experiments. The validity of the proton-proton coupling constants determination was checked by computer simulation.