Absolute configuration of 2-amino-4-phenyl butyric acid
β Scribed by Weller, Harold N.; Gordon, Eric M.
- Book ID
- 127197861
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 309 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The synthesis of the title compound is described. It involves base catalyzed substitution of deuterium for hydrogen in 3-p- -chlorophenylglutaric acid which is subsequently transformed to baclofen. The overall yield is 80%. ## INTRODUCTION AND DISCUSSION In order to develop a mass fragmentographi
The so called fast transmitters either excicatory such as glutamate and aspartate or the inhibitory neuro-transmitter 4-aminobutyric acid (GABA) are involved in a multitude of important regulatory processes in the brain.(l) It may be possible to study some of these processes using [11C]GABA in combi