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Absence of sonic hedgehog (Shh) germline mutations in patients with thyroid dysgenesis

✍ Scribed by Marina Muzza; Luca Persani; Tiziana de Filippis; Roberto Gastaldi; Maria Cristina Vigone; Davide Sala; Giovanna Weber; Renata Lorini; Paolo Beck-Peccoz; Laura Fugazzola


Book ID
108704142
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
128 KB
Volume
69
Category
Article
ISSN
0300-0664

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## Abstract ## Background Characterization of the genetic background of pediatric thyroid carcinomas could aid in distinguishing between differently staged tumors with respect to treatment and prognosis. Two known genetic factors associated with thyroid carcinoma, the proto‐oncogenes __gsp__ and _