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Absence of mutations in the WT1 gene in patients with XY gonadal dysgenesis

✍ Scribed by A. Nordenskjöld; G. Fricke; M. Anvret


Publisher
Springer
Year
1995
Tongue
English
Weight
334 KB
Volume
96
Category
Article
ISSN
0340-6717

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Mutations in the conserved domain of SRY
✍ Enikö K. Pivnick; Stephen Wachtel; Diane Woods; Joe Leigh Simpson; Colin E. Bish 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 313 KB

In order to evaluate the role of SRY in the determination of the testis, we sequenced the conserved domain of the SRY gene in 8 patients with 46,XY gonadal dysgenesis and 3 patients with related disorders, and compared our data with those obtained in 6 other similar studies. In our study, a 609-bp f