𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats

✍ Scribed by Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi

Book ID
117466747
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
111 KB
Volume
162
Category
Article
ISSN
0304-3835

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hypermethylation of the Dal-1 gene in lu
Hypermethylation of the Dal-1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
✍ Toshifumi Tsujiuchi; Tomomi Masaoka; Eriko Sugata; Mariko Onishi; Hiromasa Fujii 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB

## Abstract DAL‐1 (differentially expressed in adenocarcinoma of the lung) is an actin‐binding protein that has been shown to suppress growth in lung cancer cells. Recently, inactivation of the gene encoding DAL‐1 due to hypermethylation has been found in several human malignancies, including lung

Alterations of the Dutt1/Robo1 gene in l
Alterations of the Dutt1/Robo1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Masahiro Tsuts 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 148 KB

## Abstract Abnormalities of tumor suppressor genes (TSGs) on chromosome 3p are known to be important for the development of human lung cancers. In the present study, we investigated alterations of the __Dutt1__/__Robo1__ gene, as a possible tumor suppressor in this region, in rat lung adenocarcino

Alterations of the M6p/Igf2 receptor gen
Alterations of the M6p/Igf2 receptor gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB

## Abstract Alterations of the mannose 6‐phosphate/insulin‐like growth factor II receptor (__M6p/lgf2r__) gene were investigated in lung adenocarcinomas induced by N‐nitrosobis(2‐hydroxypropyl)amine (BHP) in rats. Male Wistar rats, 6 wk old, were given 2000 ppm BHP in their drinking water for 12 wk

Aberrant methylation patterns of the Ras
Aberrant methylation patterns of the Rassf1a gene in rat lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine
✍ Kyoko Shimizu; Ayumi Kato; Mayumi Shigemura; Hiromasa Fujii; Kanya Honoki; Toshi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 177 KB

To clarify the involvement of the Rassf1a gene in lung carcinogenesis, we investigated the methylation status in the 5 0 upstream region of the RAS-association domain family 1, isoform A (Rassf1a) gene in rat lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine (BHP). Six-week-old male

Alterations of the retinoblastoma-relate
Alterations of the retinoblastoma-related gene RB2/p130 in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats
✍ Toshifumi Tsujiuchi; Yasutaka Sasaki; Yoichi Konishi; Masahiro Tsutsumi 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB

## Abstract Alteration of the retinoblastoma‐related gene __RB2/p130__ was investigated in lung adenocarcinomas induced by __N__‐nitrosobis(2‐hydroxypropyl)amine (BHP) in male Wistar rats. At 6 wk of age, 21 animals were given 2000 ppm of BHP in their drinking water for 12 wk and then maintained wi