## Abstract Fresh nasopharyngeal carcinoma (NPC) biopsies were treated in several ways to yield satisfactory cell preparations for detection of EpsteinβBarr virus (EBV)βassociated nuclear antigen (EBNA) by antiβcomplement immunofluorescence tests. If the cells were well dispersed (trypsinization or
Absence of Nuclear p16 From Epstein-Barr Virus-Associated Undifferentiated Nasopharyngeal Carcinomas
β Scribed by Eriko Shibosawa; Kouichiro Tsutsumi; Izumi Koizuka; Masahiro Hoshikawa; Toshifumi Takakuwa
- Book ID
- 110082193
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 26 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0023-852X
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The authors thank Drs. Anthony J. Janckila and Lung T. Yam of the University of Louisville, Louisville, Kentucky, for their criticism of this article. They also would like to thank Miss Su-Huei Lee for her excellent technique for in situ hybridization and immunohistochemical stainings.
## Abstract We have investigated the association of immunoescape mechanisms in nasopharyngeal carcinoma (NPC) lesions with EpsteinβBarr virus (EBV) infection and clinical course of the disease. Tumor biopsy specimens obtained from 36 Japanese NPC patients were examined for antigen processing machin