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Absence of mutations in the β-catenin and adenomatous polyposis coli genes in papillary and follicular thyroid carcinomas

✍ Scribed by Noriko Miyake; Hiroyuki Maeta; Satoshi Horie; Yukisato Kitamura; Eiji Nanba; Kaoru Kobayashi; Tadashi Terada


Book ID
114431109
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
372 KB
Volume
51
Category
Article
ISSN
1320-5463

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The adenomatous polyposis coli (APC) gene is the target of the loss of chromosome 5q heterozygosity observed frequently in gastrointestinal tract carcinomas and is inactivated in these carcinomas. We screened 94 gastrointestinal tract carcinomas for APC mutations, by polymerase chain reaction single