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Absence of FHIT expression is associated with apoptosis inhibition in colorectal cancer

โœ Scribed by Cao, Jie ;Chen, Xiaoping ;Li, Wanglin ;Xia, Jie ;Du, Hong ;Tang, Weibiao ;Chen, Shanming ;Wang, Hui ;Chen, Xiwen ;Xiao, Huanqing ;Li, Yuyuan

Book ID
107472130
Publisher
Higher Education Press and Springer
Year
2007
Tongue
English
Weight
839 KB
Volume
1
Category
Article
ISSN
1673-7342

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## Abstract Fragile histidine triad (FHIT) is a tumor suppressor gene whose allelic loss is associated to a number of human cancers. FHIT protein acts as a diadenosine oligophosphate hydrolase, but its tumor suppressive activity appears as independent from its enzymatic activity. Tumor necrosis fac