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Absence of FHIT expression is associated with apoptosis inhibition in colorectal cancer

โœ Scribed by Jie Cao; Xiaoping Chen; Wanglin Li; Jie Xia; Hong Du; Weibiao Tang; Hui Wang; Xiwen Chen; Huanqing Xiao; Yuyuan Li


Book ID
106314529
Publisher
Springer
Year
2007
Tongue
English
Weight
747 KB
Volume
6
Category
Article
ISSN
1610-1979

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TRAIL-induced apoptosis of FHIT-negative
โœ Prisco Mirandola; Giuliana Gobbi; Ivonne Sponzilli; Chiara Malinverno; Andrea Ca ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 286 KB

## Abstract Fragile histidine triad (FHIT) is a tumor suppressor gene whose allelic loss is associated to a number of human cancers. FHIT protein acts as a diadenosine oligophosphate hydrolase, but its tumor suppressive activity appears as independent from its enzymatic activity. Tumor necrosis fac