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Absence of Effect of Stimulants on the Pharmacokinetics of Desipramine in Children

✍ Scribed by Dr. Louise Glassner Cohen; Dr. Jefferson Prince; Dr. Joseph Biederman; Dr. Timothy Wilens; Dr. Stephen V. Faraone; Dr. Sabrina Whitt; Mr. Eric Mick; Dr. Thomas Spencer; Dr. Michele C. Meyer; Mr. David Polisner; Dr. James G. Flood


Book ID
115047752
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
50 KB
Volume
19
Category
Article
ISSN
0277-0008

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Administration of terfenadine (Seldane@) immediately after a high fat breakfast slightly affects the rate but not the extent of absorption relative to fasting administration. Mean peak levels of the active metabolite were increased by 13 per cent but delayed by 0.9 h while AUC was virtually the same