Glucocorticoids inhibit the growth and promote the differentiation of normal lung cells. Transformed A5 mouse lung cells containing an activated Ki-ras gene are not responsive to glucocorticoid-induced growth inhibition and demonstrate increased cell proliferation. Activated ras genes may lead to co
Abolishment of c-fos Inducibility in ras-Transformed Mouse Osteoblast Cell Lines
β Scribed by Kiyoshi Nose; Makiko Itami; Masanobu Satake; Yoshiaki Ito; Toshio Kuroki
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 831 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0899-1987
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We previously demonstrated that after transduction with the v-Ha-ras oncogene and grafting onto nude mouse hosts, primary epidermal keratinocytes with a null mutation in the p53 gene form tumors with increased growth rates and predisposition to malignant conversion relative to p53 wild-type keratino
A rabbit antiserum (A2) directed against the detergent-solubilized fraction of the simian virus 40-transformed mouse embryo fibroblast cell line VLM detects common antigens in primary cell cultures from BALB/c mouse embryos and in transformed cell lines from various species. Positively reacting cell
DNA from five lines of transformed bladder epithelial cells derived from cultures of primary cells that had been treated with 7,12-dimethylbenz[a]anthracene (DMBA) can transform NIH 3T3 mouse fibroblasts in DNA transfection experiments. Southern analysis of DNA from NIH 3T3 primary and secondary tra
Heregulin P1 was found to stimulate the anchorage-dependent, serum-free growth of nontransformed human MCF-1 OA mammary epithelial cells. Unlike epidermal growth factor, transforming growth factor a, or amphiregulin, heregulin P I was also able to induce the anchorage-independent growth of MCF-1OA c
## Abstract We have previously shown that transcription of immediateβearly __cβfos__ protooncogene is becoming strongly repressed in rat embryo fibroblasts transformed by oncogenes __E1A__ and __cHaβras__, so that serum only slightly stimulated __cβfos__ transcription in these cells in contrast to