## Objective: Mice deficient in beta2-microglobulin (beta2m), but expressing the human major histocompatibility complex (mhc) class i molecule hla-b27, have been reported to develop spontaneous inflammatory arthritis (sa). we sought to determine whether, under certain conditions, beta2m deficiency
✦ LIBER ✦
Abnormally short serum half-lives of IgG in β2-microglobulin-deficient mice
✍ Scribed by Victor Ghetie; James G. Hubbard; Jin-Kyoo Kim; May-Fang Tsen; Yukfung Lee; E. Sally Ward
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 758 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0014-2980
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## Increased number of cytotoxic T cells within CD4+8-T cells in P2-microglobulin, major histocompatibility complex class I-deficient mice* Targeted disruption of fi2-microgobulin gene results in deficient major histocompatibility complex class I expression and failure to develop CD4-V T cells. De