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ABNORMAL GLUTAMATERGIC MECHANISMS AND BRANCHED-CHAIN AMINOACIDS IN AMYOTROPHIC LATERAL SCLEROSIS

✍ Scribed by Plaitakis, Andreas

Book ID: 122483101
Publisher: The Lancet
Year: 1989
Tongue: English
Weight: 175 KB
Volume: 333
Category: Article
ISSN: 0140-6736
DOI: 10.1016/S0140-6736(89)91170-7

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Glutamate levels were determined in the fasting plasma of 22 patients with early-stage primary amyotrophic lateral sclerosis (ALS) and compared to those of healthy and diseased controls. There was a significant increase (by approximately loo%, p < 0.0005) in the plasma glutamate of the ALS patients