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Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins

โœ Scribed by Atsushi Ikeda; Taisuke Miyazaki; Sho Kakizawa; Yasushi Okuno; Soken Tsuchiya; Akira Myomoto; Shin-ya Saito; Tetsuji Yamamoto; Tetsuo Yamazaki; Masamitsu Iino; Gozoh Tsujimoto; Masahiko Watanabe; Hiroshi Takeshima


Book ID
116295708
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
680 KB
Volume
363
Category
Article
ISSN
0006-291X

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Effect of purkinje cell loss on cerebell
โœ Dr. T. N. Seyfried; D. J. Bernard; R. K. Yu ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 483 KB

The distribution of cerebellar gangliosides was studied in adult (73 +/- 2 days) nervous (nr/nr) mutant mice which lose 50-90% of their Purkinje cells. This neuronal loss is associated with significant reductions in cerebellar weight and ganglioside concentration. The cerebellar dry weights (mg) and