ABL deletion without associated BCR–ABL in precursor B-cell acute lymphoblastic leukemia
✍ Scribed by Andy Lo; Guangyu Gu; Mingya Liu; Vaithilingam G. Dev
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 898 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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## Abstract Gene amplification is a relatively rare event in hematologic malignancies. The __ABL__ gene on chromosome band 9q34 is a proto‐oncogene and is the well‐known translocation partner of the __BCR__ gene on 22q11 giving rise to t(9;22)(q34;q11), which is the hallmark of chronic myeloid leuk