Abiotic synthesis of purines and other heterocyclic compounds by the action of electrical discharges
✍ Scribed by S. Yuasa; D. Flory; B. Basile; J. Oró
- Book ID
- 105462474
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 483 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0022-2844
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Cyclization reactions of a-ketoarylhydrazonoyl chlorides with various dinucleophiles lead to new 1,4-benzothiazine, quinoxaline, tetrahydropyrazine, thiazole, and thiadiazoline derivatives of methyl butanoate or methyl 5-oxopentanoate. The inhibition of 5-lipoxygenase (LO) was determined by monitori
## Synthesis of New Tetrahydropyrazine and Other Heterocyclic Compounds by Reaction of Hydrazonoyl Chlorides. -New cyclization reactions with hydrazonoyl chlorides (II), (V), (X) are described. Only dimerization of (X) occurs in the presence of N,N'-diphenyl thiourea. The formed arylhydrazone pro