Aberrant transcription of FHIT gene in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters
β Scribed by Tsukasa Kitahashi; Toshifumi Tsujiuchi; Kenji Satoh; Kozo Ohtsuki; Yoichi Konishi; Masahiro Tsutsumi
- Book ID
- 113607722
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 354 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0940-2993
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## Abstract Alteration of the __Fhit__ gene was investigated in pancreatic duct adenocarcinomas induced by __N__βnitrosobis(2βoxopropyl)amine (BOP) in Syrian golden hamsters. The animals received 70 mg/kg BOP, followed by repeated exposure to an augmentation pressure regimen consisting of a choline
## Abstract Alterations of the __Rassf1a__ gene were investigated in pancreatic duct adenocarcinomas (PDAs) induced by Nβnitrosobis(2βoxopropyl)amine (BOP) in hamsters. Female Syrian golden hamsters received 70 mg/kg BOP, followed by repeated exposures to an augmentation pressure regimen consisting