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Aberrant Promoter Methylation of p16 and MGMT Genes in Lung Tumors from Smoking and Never-Smoking Lung Cancer Patients

โœ Scribed by Liu, Yang; Lan, Qing; Siegfried, Jill M.; Luketich, James D.; Keohavong, Phouthone


Book ID
122193267
Publisher
Neoplasia Press
Year
2006
Tongue
English
Weight
129 KB
Volume
8
Category
Article
ISSN
1522-8002

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โœ Hans J. Grote; Viola Schmiemann; Helene Geddert; Ulrich P. Rohr; Rainer Kappes; ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 158 KB

Aberrant promoter methylation of normally unmethylated CpG-islands offers a promising tool for the development of molecular biomarkers. We investigated bronchial aspirates of patients admitted for suspected lung cancer with regard to the prevalence of aberrant methylation of potential marker genes.