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Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

✍ Scribed by Baylin, S. B.

Book ID
115492084
Publisher
Oxford University Press
Year
2001
Tongue
English
Weight
213 KB
Volume
10
Category
Article
ISSN
0964-6906

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## Abstract The homeobox gene __PROX1__ is related to the __Drosophila prospero__ gene, which is expressed in the developing central nervous system and lens‐secreting cone cells. We found that the __PROX1__ gene had missense and nonsense mutations in 4 of 29 hematologic cell lines analyzed. Decreas