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Aberrant Methylation of Preproenkephalin and p16 Genes in Pancreatic Intraepithelial Neoplasia and Pancreatic Ductal Adenocarcinoma

✍ Scribed by Noriyoshi Fukushima; Norihiro Sato; Takashi Ueki; Christophe Rosty; Kimberly M. Walter; Robb E. Wilentz; Charles J. Yeo; Ralph H. Hruban; Michael Goggins


Book ID
117021097
Publisher
American Society for Investigative Pathology
Year
2002
Tongue
English
Weight
815 KB
Volume
160
Category
Article
ISSN
0002-9440

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Aberrant methylation of Reprimo correlat
✍ Norihiro Sato; Noriyoshi Fukushima; Hiroyuki Matsubayashi; Christine A. Iacobuzi πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 267 KB πŸ‘ 1 views

## Abstract ## BACKGROUND The p53‐dependent G2/M checkpoint plays a key role in the maintenance of genomic integrity, thereby protecting cells from neoplastic progression. __Reprimo__, a gene involved in the p53‐induced G2 cell cycle arrest, has been recently identified as a novel target for aberr