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Aberrant extracellular signaling induced by ionizing radiation and its role in carcinogenesis

✍ Scribed by Rhonda L Henshall-Powell; Catherine C Park; Mary Helen Barcellos-Hoff

Book ID
117550005
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
80 KB
Volume
1236
Category
Article
ISSN
0531-5131

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To identify and compare t h e genetic lesions associated with tumorigenesis in rats carrying the mammary carcinoma suppressor (MCS) 1 gene, we induced mammary carcinomas in Wistar Furth WF) x Copenhagen (Cop))F, rats by using either 7,12-dimethylbenz[a]anthracene (DMBA) or radiation. The tumors were