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Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer’s disease

✍ Scribed by Hyoung-gon Lee; Osamu Ogawa; Xiongwei Zhu; MichaelJ. O’Neill; RobertB. Petersen; RudolphJ. Castellani; Hossein Ghanbari; George Perry; MarkA. Smith

Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
385 KB
Volume
107
Category
Article
ISSN
0001-6322

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## Abstract The group I metabotropic glutamate receptors, mGluR1 and mGluR5, exhibit a high degree of sequence homology, and are often found co‐expressed in the same neuronal populations. These receptors couple to a broad array of effector systems, and are implicated in diverse physiological and pa