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Aberrant expression of DPPA2 and HIWI genes in colorectal cancer and their impacts on poor prognosis

✍ Scribed by Raeisossadati, Reza; Abbaszadegan, Mohammad Reza; Moghbeli, Meysam; Tavassoli, Alireza; Kihara, Alexandre Hiroaki; Forghanifard, Mohammad Mahdi


Book ID
121551035
Publisher
S. Karger AG
Year
2014
Tongue
English
Weight
328 KB
Volume
35
Category
Article
ISSN
1010-4283

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## Abstract Loss of imprinting (LOI) of insulin‐like growth factor 2 (__IGF2__) is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic __IGF2__ expression correlates strongly with the hypomethylation of a differentially methylated region (D