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47. Microarray Analysis of Smad4 Gene Expression and Impact On Survival in Human Colorectal Cancer

✍ Scribed by J. Joshua Smith; Bonnie LaFleur; Kay Washington; Nipun Merchant; Robert Coffey; Jay Snoddy; Shawn Levy; Anuradha Chakravarthy; R. Daniel Beauchamp

Book ID
116703614
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
66 KB
Volume
144
Category
Article
ISSN
0022-4804

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✍ Latil, Alain; Pesche, Sandrine; ValοΏ½ri, Antoine; Fournier, Georges; Cussenot, Ol πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 229 KB πŸ‘ 2 views

BACKGROUND. Loss of heterozygosity (LOH) on chromosome arm 18q is common in sporadic prostate cancer and may be involved in cancer development through inactivation of tumor-suppressor genes (TSG). Recent identification, at 18q21.1, of MADR2/Smad2, a key component in transforming growth factor ␀ (TGF