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ABC transporters and the accumulation of imatinib and its active metabolite CGP74588 in rat C6 glioma cells

✍ Scribed by Xavier Declèves; Sébastien Bihorel; Marcel Debray; Salah Yousif; Gian Camenisch; Jean-Michel Scherrmann


Book ID
119346505
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
575 KB
Volume
57
Category
Article
ISSN
1043-6618

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## Abstract Polycyclic aromatic hydrocarbon (PAH) compounds including 3‐methylcholanthrene induce harmful reactive intermediates and reactive oxygen species. This study reports the effect of 3‐methylcholanthrene on the accumulation of vitamin C and the expression of vitamin C transporters. ODS rats