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A7.10 Genetic Variants in the IL-4 and IL-4 Receptor Genes in Association with the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts

โœ Scribed by Krabben, A.; Wilson, A.; Rooy, D. d.; Zhernakova, A.; Brouwer, E.; Lindqvist, E.; Saxne, T.; Stoeken, G.; Nies, J. v.; Knevel, R.; Huizinga, T.; Koeleman, B.; Toes, R.; Gregersen, P.; Helm-van Mil, A. v. d.


Book ID
121341258
Publisher
BMJ Publishing Group
Year
2013
Tongue
English
Weight
71 KB
Volume
72
Category
Article
ISSN
0003-4967

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## Abstract ## Objective Cytotoxic T lymphocyteโ€“associated antigen 4 (CTLAโ€4) is a negative regulator of T cells and is, therefore, a strong candidate susceptibility gene for T cellโ€“mediated autoimmune diseases. The association of CTLAโ€4 singleโ€nucleotide polymorphisms (SNPs) with rheumatoid arthr