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A variant of the IL4 I50V single-nucleotide polymorphism is associated with erosive joint disease in psoriatic arthritis

✍ Scribed by Proton Rahman; Tara Snelgrove; Lynette Peddle; Fiotos Siannis; Vernon Farewell; Cathy Schentag; Dafna Gladman


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
45 KB
Volume
58
Category
Article
ISSN
0004-3591

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✍ Timothy R. D. J. Radstake; Barbara Franke; Mark H. Wenink; Karin C. A. M. Nabbe; πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 151 KB πŸ‘ 1 views

## Abstract ## Objective FcΞ³ receptors (FcΞ³Rs) recognize immune complexes (ICs) and coordinate the immune response by modulating the functions of dendritic cells (DCs). The purpose of this study was to unravel the role of the inhibitory FcΞ³RIIb in rheumatoid arthritis (RA) by studying the effect o