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A23 EXPRESSION OF HTRA1 IN HUMAN OA CHONDROCYTES LEADS TO MATRIX DEGRADATION INHIBITION OF MATRIX SYNTHESIS AND THE EXPRESSION OF A HYPERTROPHIC PHENOTYPE

✍ Scribed by P.G. Mitchell; M.A. Carozza; J. Brittain; D.D. McKinley; K.L. Duffin; E. Zhen; S. Chandrasekhar; Y-W. Qian; A. Boodhoo


Book ID
114350655
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
102 KB
Volume
16
Category
Article
ISSN
1063-4584

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## Abstract The objective of this article was to investigate the role and expression of a novel adipocytokine, angiopoietin‐like‐4 (ANGPTL4), in arthropathy. Human chondrocytes were obtained from articular cartilage of patients with rheumatoid arthritis (RA) and osteoarthritis (OA), who underwent t