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A092 RMPT in Relapsed/Refractory Multiple Myeloma: Results of a Multicenter Phase II Clinical Trial

โœ Scribed by Palumbo, A; Larocca, A; Sanpaolo, G; Falcone, AP; Federico, V; Canepa, L; Crugnola, M; Baldini, L; Magarotto, V; Falco, P; Petrucci, MT; Boccadoro, M


Book ID
118629231
Publisher
CIG Media Group, LP.
Year
2009
Tongue
English
Weight
111 KB
Volume
9
Category
Article
ISSN
1557-9190

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Phase II trial of temsirolimus in patien
โœ Sherif S. Farag; Shuhong Zhang; Buffy S. Jansak; Xiaojing Wang; Eric Kraut; Kenn ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 508 KB

In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat