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A β-Peptide Reverse Turn that Promotes Hairpin Formation

✍ Scribed by Chung, Yong Jun; Christianson, Laurie A.; Stanger, Heather E.; Powell, Douglas R.; Gellman, Samuel H.

Book ID
126014244
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
92 KB
Volume
120
Category
Article
ISSN
0002-7863

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✍ Rajkishor Rai; Srinivasarao Raghothama; Rajagopalan Sridharan; Padmanabhan Balar 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 553 KB

## Abstract Designed octapeptides Boc‐Leu‐Val‐Val‐Aib‐^D^Xxx‐Leu‐Val‐Val‐OMe (^D^Xxx = ^D^Ala, 3a;^D^Val, 3c and ^D^Pro, 5a) and Boc‐Leu‐Phe‐Val‐Aib‐^D^Ala‐Leu‐Phe‐Val‐OMe (3b) have been investigated to construct models of a stable type I′ β‐turn nucleated hairpin and to generate systems for invest