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A New Turn Structure for the Formation of β-Hairpins in Peptides

✍ Scribed by Nowick, James S.; Brower, Justin O.

Book ID
126808688
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
115 KB
Volume
125
Category
Article
ISSN
0002-7863

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Tuning the β-turn segment in designed pe
Tuning the β-turn segment in designed peptide β-hairpins: Construction of a stable type I′ β-turn nucleus and hairpin–helix transition promoting segments
✍ Rajkishor Rai; Srinivasarao Raghothama; Rajagopalan Sridharan; Padmanabhan Balar 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 553 KB

## Abstract Designed octapeptides Boc‐Leu‐Val‐Val‐Aib‐^D^Xxx‐Leu‐Val‐Val‐OMe (^D^Xxx = ^D^Ala, 3a;^D^Val, 3c and ^D^Pro, 5a) and Boc‐Leu‐Phe‐Val‐Aib‐^D^Ala‐Leu‐Phe‐Val‐OMe (3b) have been investigated to construct models of a stable type I′ β‐turn nucleated hairpin and to generate systems for invest