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A YAC contig encompassing the 11q14.3 breakpoint of a translocation associated with schizophrenia, and including the tyrosinase gene

✍ Scribed by Joëlle Petit, Pierre Boisseau, Laurence Taine, Bruno Gauthier, Benoit Arveiler


Book ID
113034924
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
354 KB
Volume
10
Category
Article
ISSN
0938-8990

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Using a series of yeast artificial chromosomes (YAC) from the 8p I I -I 2 chromosome region, we have analyzed a t(822) translocation present in two patients suffering from acute leukemia by using fluorescence in situ hybridization (FISH). We have identified a YAC that spans the breakpoint in both ca