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A water-soluble analog of triptolide induces ovarian cancer cell death in vitro and in vivo

✍ Scribed by Hunt, C. Rivard; Geller, M.; Evans, C.; Vogel, R.; Ramakrishnan, S.; Saluja, A.


Book ID
122873676
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
96 KB
Volume
130
Category
Article
ISSN
0090-8258

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## Abstract A hallmark of cancer cells is an ability to evade apoptosis. Overexpression and/or activating mutations of prosurvival molecules such as the X‐linked inhibitor of apoptosis (XIAP) contribute to this inappropriate cell survival. Our objectives were to investigate the effects of downregul