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A versatile synthesis of functionalised 2-aminoquinolines by mercury controlled cyclisation of 2-vinylphenylthioureas

✍ Scribed by Kenneth J. Wiggall; Stewart K. Richardson


Book ID
112131260
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
296 KB
Volume
32
Category
Article
ISSN
0022-152X

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A novel one-pot synthesis of 2-aminoquin
✍ Ramiya R. Amaresh; Paramasivan T. Perumal πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 784 KB

Studies have been carried out on a new novel method for the synthesis of 2-(N,Ndisubstituted)aminoquinoline via intramolecular electrophilic substitution of methyleniminium salts by azide. Treatment of l-(2-azidophenyl)ethanone with Vilsmeier reagent (DMF/POC13) gave 4-chloro-2dimethylamino-3-quinol