Glycosyl fluorides remain popular for a variety of synthetic and experimental applications largely because they are much more stable than other glycosyl halides. This stability results from the high energy of the glycosidic C-F bond relative to its brominated or chlorinated counterparts [1], and per
A versatile one-pot procedure for the insertion of a 3-substituent into 2-cycloalkenones
β Scribed by Alan R. Katritzky; Jadwiga Soloducho; Richard P. Musgrave; Jaco C. Breytenbach
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 190 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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A one-pot combination of a modified FriedlΓ€nder annulation and a Knoevenagel condensation provides 2styrylquinolines in good to excellent yields. A variety of substrates are reacted in one-pot in the presence of 1-methylimidazolium trifluoroacetate ([Hmim]TFA).
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