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A versatile intermediate, d-4,5-bis(dibenzyl phosphoryl) -myo-inositol derivative for synthesis of inositol phosphates. Synthesis of 1,2-cyclic-4,5-,1,4,5-, and 2,4,5-trisphosphate

✍ Scribed by Yutaka Watanabe; Tomio Ogasawara; Hiroyuki Nakahira; Tomoko Matsuki; Shoichiro Ozaki


Book ID
108381763
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
256 KB
Volume
29
Category
Article
ISSN
0040-4039

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A chemoenzymatic synthesis of d-myo-inos
✍ Lei Ling; Shoichiro Ozaki πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 English βš– 816 KB

Enzyme-catalyzed esterification of racemic 2,3-O-cyclohexylidene-myo-inositol (DL-1) proceeded exclusively in 1,4-dioxane to give optically pure L-1-O-acetyl-2,3-O-cyclohexylidene-myo-inositol (L-2) and D-2,3-O-cyclohexylidene-myo-inositol (D-1). A new practical route has been developed for the synt