Iontophoretic transdermal delivery of sumatriptan was investigated in vitro. Among the conditions tested, 0.25 mA/cm 2 and low ionic strength (NaCl 25 mM) was the best experimental condition to increase its transport across the skin. The flux increased 385-fold respective to passive diffusion, thus
A Unique Iontophoretic Patch for Optimal Transdermal Delivery of Sumatriptan
✍ Scribed by Steven J. Siegel; Carol O’Neill; Louise M. Dubé; Peter Kaldeway; Russell Morris; David Jackson; Terri Sebree
- Publisher
- Springer US
- Year
- 2007
- Tongue
- English
- Weight
- 221 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0724-8741
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