A total synthesis of mycophenolic acid
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AdriΓ‘n Covarrubias-ZΓΊΓ±iga; Armando GonzΓ‘lez-Lucas
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Article
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1998
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Elsevier Science
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French
β 107 KB
A total convergent synthesis of mycophenolic acid 1 from 2-geranyldimethyl-l,3-acetonedicarboxylate 2 and 4-pivaloyloxy-2-butynal using a Michael addition-Dieckmann cyclization as key step is described.