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A total synthesis of a stage specific pentasaccharide embryogenesis marker

✍ Scribed by Tae Kyo Park; In Jong Kim; Samuel J. Danishefsky


Book ID
103400743
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
243 KB
Volume
36
Category
Article
ISSN
0040-4039

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Total synthesis of a heparin pentasaccha
✍ Pierre SinaΓΏ; Jean-Claude Jacquinet; Maurice Petitou; Philippe Duchaussoy; Isido πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 English βš– 254 KB

Heparin is a sulfated glucosaminoglycan with a well-known anticoagulant activity' , and the active molecules have a high affinity for antithrombin III (AT-III), thereby enhancing the effects of this inhibitor on procoagulant proteases. The structures of highaffinity oligosaccharides, prepared from h