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A Three-Step Preparation of MAC Reagents from Malononitrile.

✍ Scribed by Hisao Nemoto; Xinming Li; Rujian Ma; Ichiro Suzuki; Masayuki Shibuya

Book ID
101939662
Publisher
John Wiley and Sons
Year
2003
Weight
106 KB
Volume
34
Category
Article
ISSN
0931-7597

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A three-step preparation of MAC reagents
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An alternative method for the preparation of MAC reagents, H-C(CN) 2 O-R, was developed. Using the proposed method, MAC reagents with acyl moiety were synthesized from malononitrile in more than 60% overall yields in three steps.

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