A theoretical analysis of specificity of nucleic acid interactions with oligonucleotides and peptide nucleic acids (PNAs)
โ Scribed by Aleksey Lomakin; Maxim D Frank-Kamenetskii
- Book ID
- 115628320
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 326 KB
- Volume
- 276
- Category
- Article
- ISSN
- 0022-2836
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Coulombic interactions between the side chains of charged amino acids (Arg + , Lys-, and H i s + ) and negatively charged phosphate groups of nucleic acid fragments have been studied theoretically. Diribose monophosphate and dideoxyribose monophosphate a r e chosen as model systems for single-strand